Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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106
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120
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60,522
results
106
R&D Systems™ ESI 05
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Epac2 inhibitor
| CAS | 5184-64-5 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 1,3,5-Trimethyl-2-[(4-methylphenyl)sulfonyl]benzene |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C16H18O2S |
107
R&D Systems™ FHT 2344
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent SMARCA2/4 inhibitor
109
R&D Systems™ CDK8/19i
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent and selective CDK8 and CDK19 inhibitor; maintains pluripotency of mouse PSCs in culture
| Target | Cyclin-dependent Kinase Inhibitors |
|---|---|
| CAS | 923596-52-5 |
| Purity | 0.98 |
| Chemical Name or Material | N-Propyl-3-(4-pyridinyl)imidazo[1,2-b]pyridazin-6-amine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C14H15N5 |
110
R&D Systems™ PSEM 308 hydrochloride
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. PSAML141F-GlyR and PSAML141F,Y115F-5-HT3 chimeric ion channel agonist
| Target | Pharmacologically Selective Effector Molecules/PSEM |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 5-Methyl-5,8,9,10,11 A,12-hexahydro-4 H-8,11-ethanopyrido[3 ',2 ':3,4 ]diazepino[6,7,1-hi]indole hydrochloride |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C17H21N3.HCl |
| Formula Weight | 303.83 |
111
R&D Systems™ SNIPER(ER)-87
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent and selective ERα Degrader (SNIPER)
112
R&D Systems™ PZM21
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Selective μ receptor agonist
| Target | mu Opioid Receptor Agonists |
|---|---|
| CAS | 1997387-43-5 |
| Purity | 0.98 |
| Chemical Name or Material | N-[(2 S)-2-(Dimethylamino)-3-(4-hydroxyphenyl)propyl]-N'-[(1 S)-1-methyl-2-(3-thienyl)ethyl]urea |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C19H27N3O2S |
113
R&D Systems™ TL 12-186
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Multikinase Degrader (PROTAC™)
114
R&D Systems™ Thalidomide 4'-ether-alkylC4-acid
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Cereblon ligand with alkyl linker and terminal acid for onward chemistry
115
R&D Systems™ TM 38837
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Highly potent CB1 inverse agonist; peripherally restricted
116
R&D Systems™ RU.521
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS)
| Target | Synthase/Synthetase Inhibitors |
|---|---|
| CAS | 2262452-06-0 |
| Purity | 0.98 |
| Chemical Name or Material | 3-[1-(6,7-Dichloro-1 H-benzimidazol-2-yl)-5-hydroxy-3-methyl-1 H-pyrazol-4-yl]-1(3 H)-isobenzofuranone |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C19H12Cl2N4O3 |
117
R&D Systems™ Pomalidomide 4'-alkylC2-azide
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. Cereblon ligand with alkyl linker and terminal azide for onward chemistry
118
R&D Systems™ JHU 37160
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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A Tocris product, part of R&D Systems. High affinity and highly potent hM3Dq and hM4Di DREADD agonist; blood brain barrier penetrant
| Target | DREADD Activators |
|---|---|
| CAS | 2369979-68-8 |
| Purity | 0.98 |
| Chemical Name or Material | 8-Chloro-11-(4-ethylpiperazin-1-yl)-4-fluoro-5 H-dibenzo[b,e][1,4 ]diazepine |
| Recommended Storage | Store at RT |
| Molecular Formula | C19H20ClFN4 |
120
| Target | Ferroptosis Inhibitors |
|---|---|
| CAS | 862808-01-3 |
| Purity | 0.98 |
| Chemical Name or Material | 3-(4-Bromophenyl)-6-((4-(4-methoxyphenyl)piperazin-1-yl)methyl)thiazolo[2,3-c][1,2,4]triazole |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C22H22BrN5OS |